Usual care is defined as best-practice, guideline-directed therapy of AFib, including but not limited to (a) stroke prevention therapy, (b) rate-control, and (c) treatment of risk factors. More specifically, oral anticoagulation in those men with a CHA2DS-2VASc score of 2 or greater or women with a CHA2DS-2VASc score of 3 or greater, rate control, and treatment of concomitant cardiovascular conditions (e.g., coronary artery disease or heart failure).